• Limited data exist concerning the

  2019-04-26

  

  Limited data exist concerning the long-term incidence and prognosis of LJI308 failure after myocardial infarction, particularly in the era of coronary revascularization. New-onset heart failure significantly increases the mortality risk among these patients [23]. Current ICD trials have shown that t

• br Introduction Percutaneous transcatheter device closure of

  2019-04-25

  

  Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective

• In a study of the

  2019-04-25

  

  In a study of the atrial pacing preference (APP) algorithm, Ogawa et al. [12] randomly programmed pacemakers as APP OFF and APP ON at 3 different settings (8, 16, and 33 cycles). The authors found that the most effective setting differed according to the patient and thus concluded that this therapy

• br Methods br Results br Discussion Bisphosphonates reduce s

  2019-04-25

  

  Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve

• The comparative consensus modelling approach used

  2019-04-25

  

  The comparative consensus modelling approach used by Eaton and colleagues is now used frequently to justify the implementation of particular HIV interventions. However, this approach produces meaningful results only if the comparison is based on valid models. Most comparative consensus studies (inc

• br Malaria is a major public

  2019-04-25

  

  Malaria is a major public health problem and a leading cause of mortality worldwide, especially in sub-Saharan Africa, where 90% of the world\'s 627 000 malaria deaths occur every year. However, the disease is usually curable if diagnosed quickly. Diagnosis is often made on the basis of clinical s

• br Al hablar del requisito sine qua non de conocer

  2019-04-25

  

  Al hablar del requisito sine qua non de conocer la lengua uitoto, vale la pena hacer un paréntesis para repasar el estado de los estudios propiamente lingüísticos. Diferentes recuentos bibliográficos sobre las fuentes para el estudio de las lenguas de la Amazonia colombo-peruana, reportan que los

• br Conflict of interest statement br

  2019-04-24

  

  Conflict of interest statement Acknowledgments The authors would like to thank Dr. Bjørn Naume, and Dr. Erik Løkkevik from the Department of Clinical Oncology, the Norwegian Radium Hospital for their helpful comments. This study was supported by grants from the Norwegian Radium Hospital Founda

• Depending on the target gene KLF may function

  2019-04-24

  

  Depending on the target gene, KLF4 may function as both a repressor and activator of transcription [31,32]. Previous studies demonstrated Bax could be a tumor-suppressor target of KLF4 functioning as an anti-oncogene [33,34]. When transfected with anti-miR-367, MG-63 and U2OS ceramide kinase showed

• br Health research consortia in sub Saharan Africa present

  2019-04-24

  

  Health research consortia in sub-Saharan Africa present a positive outlook for the region through increased scientific capacity. New networks of African–African, African–European, and African–global partnerships provide platforms to advance crucial research domains. Such networks enable junior Afr

• Ante estas opiniones hay que tomar en cuenta que investigaci

  2019-04-24

  

  Ante estas opiniones, hay que tomar en cuenta que: “investigaciones recientes muestran que los pueblos indígenas han emergido junto herpes simplex virus procesos de revitalización étnica y cultural, que han transformado el escenario sociopolítico y han puesto en tela de juicio las antiguas conceptua

• smo inhibitor In addition to the effect of vector control ag

  2019-04-23

  

  In addition to the effect of vector control against malaria and HAT on lymphatic filariasis endemicity over several years, recent improvements in NTD mapping strategies and diagnosis of have greatly affected the outcomes of surveys undertaken to establish the burden of NTDs in Africa. More accurate

• Our group then carried out a study to determine the

  2019-04-23

  

  Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else

• Cisplatin based chemotherapy is commonly used in adjuvant CC

  2019-04-23

  

  Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo

• The review Bile acid receptor link nutrient sensing to metab

  2019-04-23

  

  The review “Bile pi3k inhibitor receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic, but

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