• Finally in the context of this adipose specific FABP transge

  2018-11-14

  

  Finally, in the context of this adipose specific FABP4 transgenic (over expression) mouse model phenotype, it is essential to discuss the caveats of this animal model. In the last five years several reviews have highlighted the advantages and disadvantages of the different promoters (for example FAB

• The gene therapy group had a trend towards fewer ranibizumab

  2018-11-14

  

  The gene therapy group had a trend towards fewer ranibizumab retreatments than the control group, and in a post hoc analysis 11 (53%) gene therapy patients received ≤2 ranibizumab retreatments, with the majority having improved vision. A cohort of the gene therapy group received >2 ranibizumab retre

• Glycoproteins have an important role in

  2018-11-14

  

  Glycoproteins have an important role in inflammation, and their synthesis and secretion increases during inflammatory processes (Connelly et al., 2016). We observed that the levels of circulating glycoproteins were higher in patients with pneumonia than in those without. Patients who developed VAP h

• rVSV ZEBOV serotype Indiana is genetically modified

  2018-11-14

  

  rVSV-ZEBOV (serotype Indiana) is genetically modified to encode Ebola glycoprotein (GP) instead of the VSVwildtype GP (Geisbert and Feldmann, 2011). Several animal models revealed protection after lethal challenges with EBOV (Wong et al., 2014; Jones et al., 2005; Marzi et al., 2016; de Wit et al.,

• Our group has recently reported the prevalence of co recepto

  2018-11-14

  

  Our group has recently reported the prevalence of co-receptor tropism of the archived viral strains at the time of primary infection using MPS data from 45 recently infected Brazilian first-time blood donors [9]. In continuation with our previous study, here, we assessed the prevalence of virus co-r

• br Data analysis Annotation of upstream kinase was done usin

  2018-11-14

  

  Data analysis Annotation of upstream kinase was done using the reported minimal consensus motifs for each kinase [1] and using KinomeXplorer (http://kinomexplorer.info) [10]. This information is annotated in Supplementary Table S1. Simple data analysis of this table can be performed using Microso

• br Acknowledgements br Data The concentration levels

  2018-11-14

  

  Acknowledgements Data The concentration levels of urinary metal summarized in Tables 1 and 2. Table 1 shows the concentration of metal measured in two areas. Detection limits (LOD) of each metal is also shown in Table 1. Table 2 presents data in sex groups in polluted area. All metal levels ar

• br Experimental design materials and methods Animal procedur

  2018-11-14

  

  Experimental design, materials and methods Animal procedures were approved by the Bioethical Committee at the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences. An adult male Wistar rat was imaged in vivo on a 11.7T horizontal-bore animal MRI scanner (Bi

• br Conflict of interest br Acknowledgements This study

  2018-11-14

  

  Conflict of interest Acknowledgements This study was supported by the Dutch Health Care Research Organization (ZON-Mw; 60-600-97-172) and a Vici grant 453-08-001 from the Dutch National Science Foundation (N.W.O.) awarded to prof. Dr. Reinout W. Wiers. Introduction Alcohol use typically be

• br In this issue of

  2018-11-14

  

  In this issue of , two articles revisit a pair of seminal models that have permeated developmental neuroscience research focused on adolescence. Shulman and colleagues (2016) “review, reappraise, and reaffirm” research relevant to dual-systems models of adolescent development, while Nelson and col

• br Methods br Results br Discussion br

  2018-11-13

  

  Methods Results Discussion Conclusions According to our knowledge, this ochratoxin a is the first study that investigates directed connectivity during word reading in 9-year old typically reading and dyslexic children with different levels of reading dysfluency. Our results point to dif

• Our data also show an enhancement of the P

  2018-11-13

  

  Our data also show an enhancement of the P300 component over central electrodes in response to laughing voices. This finding is consistent with previous ERP research using emotional speech showing a greater mid-latency positivity in response to happy speech when compared to angry speech (Grossmann e

• Conquistador Y a las ni

  2018-11-13

  

  Conquistador: ¿Y auda las niñas? Barbie: Son más fáciles de tratar y tan pequeñas que no podrán probar que han sido esclavizadas. Engancharemos millones por todos los continentes. Conquistador: ¡La conquista global! No suena mal. Tendremos que ser un poco violentos, pero coño, las ganancias lo jus

• br Materials and methods br Results and

  2018-11-13

  

  Materials and methods Results and discussion Conclusion We experimentally determined the system linearity over more than three orders of magnitudes using both dried samples and solution. A lower detection limit of 100fM was experimentally measured in 12μl of solutions, demonstrating a senso

• Having all kernel values available as files

  2018-11-13

  

  Having all kernel values available as files on hard disk, it is possible to implement different serial or parallelized realizations of setting up and solving the (large) regularized system of linear sensitivity equations (e.g. by factorization methods or conjugate-gradient solvers) in an iteration o

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