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Experiments on blastomere tracking performed in our
2018-11-02
Experiments on blastomere tracking performed in our study evidenced that blastomeres from 129/Sv×C57Bl/6F1 strain seem to be more sensitive to DiI labeling treatment as reported by Piotrowska et al. (2001) in C57Bl/6×CBA F1 embryos. 2/3E blastomeres were preferentially allocated to the TE whereas 2/
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It is a generally accepted that adult repopulating HSCs appe
2018-11-02
It is a generally accepted that adult-repopulating HSCs appear at E10.5–11 (Gekas et al., 2005; Medvinsky et al., 2011). At this stage, HSCs are considered to be rare and estimated to be less than one per single entire embryo (Gekas et al., 2005; Taoudi et al., 2008). A dramatic increase in the numb
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In a search for epigenetic factors regulating chromatin remo
2018-11-02
In a search for epigenetic factors regulating chromatin remodeling and MaSC maintenance, we found BPTF, which is known to regulate the accessibility of DNA and stabilize the recruitment of the NURF complex to promoter regions (Li et al., 2006; Ruthenburg et al., 2011). BPTF is essential for mouse em
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Zim in the Peg imprinted region seemed
2018-11-02
Zim1 in the Peg3 imprinted region seemed to be more preferentially expressed from the maternal allele for four iPS clones (L7, S4D, D36 and E7D) in the buy bupropion hydrochloride differentiated as EBs than in the iPS cells differentiated on gelatin-coated plates (compare Fig. 7A with Figs. 8S and
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In summary direct observation of human BMSC division
2018-11-02
In summary, direct observation of human BMSC division indicates that within a given passage, larger 4-ap are neither a distinct, replicating subpopulation nor solely an older subpopulation that has become larger with increased in vitro passaging. Instead, the larger cells represent a collection of
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Recent studies have proposed the involvement of CSCs
2018-11-02
Recent studies have proposed the involvement of CSCs/progenitor prostaglandin receptor in cancer initiation, progression, metastasis and therapy failure (Cariati and Purushotham, 2008; Gonzalez-Sarmiento and Perez-Losada, 2008; Lawson et al., 2009; Liu et al., 2005; Lynch et al., 2006; Ponti et al.
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Proper functioning of the RPE
2018-11-02
Proper functioning of the RPE is important for maintaining the health and integrity of the outer retina, photoreceptors, and choriocapillaris. Healthy RPE cells play many crucial roles in the retina, including transportation of nutrients such as glucose or vitamin A from blood to the photoreceptors,
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aldose reductase DENV has also been shown to counteract IFN
2018-11-02
DENV has also been shown to counteract IFN signaling in the infected cells, mainly through the expression of NS5 and NS4B (Munoz-Jordan et al., 2005; Ashour et al., 2009; Morrison et al., 2013). We indeed observed lessened ISG induction in the infected aldose reductase but not in the uninfected cel
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Our screening strategy permitted identification of two allel
2018-11-02
Our screening strategy permitted identification of two p53 tumor suppressor of Rbf, a core cell-cycle regulator required for metamorphosis and survival, which would be precluded from sterility-based screens. The overproliferating germ cells present in the Rbf null allele did not divide synchronousl
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To unveil the underlying molecular mechanisms
2018-11-02
To unveil the underlying molecular mechanisms by which miR-375 promotes hASC osteogenesis, we conducted a microarray analysis 7 days after osteoinduction. According to the microarray profiles, the osteogenesis-associated genes RUNX2 (ratio = 1.6431) and ALP (ratio = 1.6367) were upregulated, and DEP
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TSC haploinsufficient astrocytes presented a high proliferat
2018-11-02
TSC haploinsufficient astrocytes presented a high proliferation rate and an increased saturation density when compared with WT astrocytes. Similarly, the conditional disruption of TSC1 in astrocytes using a human GFAP-Cre system was shown to produce mice that presented with astrocytosis (Han and Sah
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Belinostat The operator form of the expression for the inter
2018-11-02
The operator form of the expression for the interaction amplitude can be written in RPAE as [5]: This expression can also be written in the matrix form as where This expression can be also represented by diagrams, as shown in Fig. 1[5,6]. If the exchange terms are taken out of the sum of Exp
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br The technical characteristics of the
2018-11-02
The technical characteristics of the equipment used for solving the problems that arise in studying various processes and phenomena occurring in the geosphere, such as the nature of the emergence and development of crustal deformation variations, are of high importance. Laser deformographs of diff
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glycine transporter br The corresponding number of trajector
2018-11-02
The corresponding number of trajectories is ten at h=3d= 1.2mm, and the ‘useful’ area increases: After choosing relative position of the emitter and lens end, calculations were done of how to transport and focus the beam by the lens. It was again implemented with the use of the program ‘Simion7
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br Introduction Studying the properties of
2018-11-02
Introduction Studying the properties of ferroelectric materials introduced into nanoporous matrices is an important problem in modern physics. The interest in ferroelectric nanocomposites based on porous matrices is primarily due to the opportunities for practical application that these materials
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