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br Conclusion br Conflict of interest br Acknowledgements br
2024-07-03
Conclusion Conflict of interest Acknowledgements Introduction Human salivary aldehyde dehydrogenase (hsALDH) (E.C. 1.2.1.5) is the first line of defence against toxic aldehydes in the oral cavity. HsALDH is primarily a dimeric, class 3 ALDH (ALDH3A1) specific for aromatic and long/medium
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br Methods br Results br Discussion First the cells isolated
2024-07-02
Methods Results Discussion First, the mtor inhibitor isolated from non-PD TA tissue and PD plaque tissue were characterized. The results showed that both cell groups were positive for vimentin and negative for desmin suggesting that these cells were fibroblasts. It was also observed that t
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We aim to evaluate the AK in regulating adenosine
2024-07-02
We aim to evaluate the AK in regulating adenosine signaling in the retina. It was reported that the degree of 4-P-PDOT injury directly depends on expression levels of AK and the resulting extracellular levels of adenosine (Boison, 2006). Indeed, transgenic mice overexpressing AK are highly suscepti
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br Introduction Adenosine deaminase ADA also known as adenos
2024-07-02
Introduction Adenosine deaminase (ADA), also known as adenosine aminohydrolase, is a key enzyme involved in the purine metabolism that converts adenosine to inosine irreversibly (Lupidi et al., 1997). It is a zinc containing metalloenzyme present in both prokaryotes and eukaryotes. In humans ADA
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Introduction Dementia is a common disease in the elderly and
2024-07-02
Introduction Dementia is a common disease in the elderly, and a significant source of disability, healthcare spending, and long-term care admissions. There is evidence to suggest that testosterone plays a role in cognitive functioning, and lower serum levels correlate with higher amyloid deposits (
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In our bioinformatics analysis of proteins with increased
2024-07-02
In our bioinformatics analysis of proteins with increased SUMOylation upon treatment with MMC and HU, we found clusters of co-regulated proteins that are known to function together in the RS response. In addition to the ATR activation proteins, BRCA1 and BARD1, we also found Fanconi anemia proteins
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A large number of studies have shown that oxidative stress
2024-07-02
A large number of studies have shown that oxidative stress is involved in the pathophysiological process of ventricular remodeling and is associated with left ventricular dysfunction (Hori and Nishida, 2009, Lord et al., 2010). The generation of reactive oxygen species (ROS) that exceeds anti-oxidat
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We also explored the possibility that this PKC
2024-07-02
We also explored the possibility that this PKC-θ activating protein could operate on the auto-phosphorylation process of the kinase, a specific event accompanying PKC activation [32]. The heated PKC-θ immunoprecipitate from metaphasic cells was then added to PKC-θ isolated both from interphasic or m
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In Pham et al employed the
2024-07-02
In 2014, Pham et al. [22] employed the microsphere-based technology to create a Luminex probe-based assay for the rapid identification of single nucleotide polymorphisms that are known to confer resistance to one or more echinocandins in C. glabrata. The targets for the FKS probes were generated usi
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The zinc transporter proteins are members of
2024-07-02
The zinc transporter proteins are members of the SLC superfamily of metal transporters, and comprise two structurally and functionally different groups, the zinc-importer (ZIP; Zrt-, Irt-like proteins) family (SLC39A), which regulate zinc transport into the cytoplasm from outside the cell and from i
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Moreover a multiple regression analysis using the year MMSE
2024-07-02
Moreover, a multiple regression analysis using the 1-year MMSE score as a dependent variable was conducted. The result showed that serum Varlitinib levels at admission did not affect the MMSE score 1 year later (β = 0.10, p = 0.639). Discussion In this study, serum Aβ42 levels were significantly
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br Materials and methods br Results
2024-07-01
Materials and methods Results Discussion Prostate cancer is the most common cancer in men in the United States and the second leading cause of cancer death. Therapeutic interventions include mainly: radical prostatectomy or radiation therapy (RT), with or without androgen deprivation therap
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There are two ways to transport FFAs
2024-07-01
There are two ways to transport FFAs into cells. First by passive diffusion. Second as the putative long-chain fatty urat1 inhibitor transporters are proposed, CD36 the plasma membrane-associated fatty acid-binding protein (FABPpm) and fatty acid transport proteins (FATP) [11], where CD36 is respon
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br ABCA is a sterol responsive gene The first evidence
2024-07-01
ABCA2 is a sterol-responsive gene The first evidence to demonstrate that ABCA2 expression responded to sterol loading was provided in an experiment involving monocyte to macrophage differentiation in vitro. Upon sterol loading with enzymatically degraded LDL (eLDL), ABCA2 expression increased onl
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br Actin at presynapses br Conclusion Thanks to the
2024-07-01
Actin at presynapses Conclusion Thanks to the recent discovery of rings, hotspots and trails, axonal CD 1530 sale is back in the spotlight. These are exiting times for neuronal cell biologists armed with constantly improving labeling and imaging techniques to observe, quantify and perturb thes
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