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Introduction Rapeseed oil production is
2023-08-23

Introduction Rapeseed oil production is very important not only because of its application in food industry, but also in petrochemical branch. Additionally, post-extraction meal and bagasse from oilseed rape are important sources of proteins in animal feedstuffs production. Oilseed rape (Brassica n
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br Acknowledgements br Introduction Microbial enzymes have
2023-08-23

Acknowledgements Introduction Microbial enzymes have gained interest for their widespread uses in industries and medicine owing to their stability, catalytic activity, and ease of production and optimization than plant and animal enzymes (Singh et al., 2016). Microbial aminopeptidases (amino-a
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Bleomycin Sulfate br Preliminary remarks Expression of the t
2023-08-22

Preliminary remarks Expression of the transcription factor aryl hydrocarbon receptor (AHR) and the AHR-repressor (AHRR) are both strikingly high in the Bleomycin Sulfate of barrier organs skin and gut [1,2]. It is generally assumed that this reflects their role in linking environmental factors to
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br Conclusion br Conflict of
2023-08-22

Conclusion Conflict of Interest Author Contributions Acknowledgements This work was supported by a research grant (SR/50/AS-14/2012) from the Department of Science and Technology, New Delhi, India to CMC and CSIR Senior Research Fellowship (09/013(0339)/2010-EMR-I) to SB. Introduction
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Whether similar mechanisms play a role in adiponectin signal
2023-08-22

Whether similar mechanisms play a role in adiponectin signal transduction and whether additional proteins are recruited to adiponectin receptors via APPL1 has not been analysed so far. Although it has been clearly established that APPL1 is a downstream adaptor protein in adiponectin signal transduct
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The same applies also to intermediate formally obtained
2023-08-22

The same applies also to intermediate , formally obtained by elimination of the R substituent from compound . If compared to the thienopyrimidine derivatives (series , C), the thieno[3,2-]pyridazin-5(4H)-ones – explored herein seem to maintain similar size and shape and also analogue structural char
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Actin is capable of polymerizing spontaneously However this
2023-08-22

Actin is capable of polymerizing spontaneously. However, this process is relatively slow and kinetically unfavorable in cells. Formation of YM178 dimers and trimers, which can easily disassemble due to their instability, is a rate-determining step in actin polymerization [5], [6]. The shape and the
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br Results br Discussion The present study uncovers a
2023-08-22

Results Discussion The present study uncovers a role of calpain, a family of calcium-dependent protease, in regulating postsynaptic differentiation at the NMJ. Cholinergic activation stimulates calpain, whose inhibition stabilizes AChR clusters in cultured muscle glutamate receptor and in agr
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The purpose of the present study is to characterize
2023-08-22

The purpose of the present study is (1) to characterize AChE from the monogonont B. koreanus and to analyze the modulation of the AChE activity and its transcription level after exposure to six pharmaceuticals, (2) to evaluate the usefulness of AChE as a molecular biomarker upon pharmaceutical expos
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To reconstruct the amino acid sequence of an ancestral subun
2023-08-22

To reconstruct the amino JNJ-26854165 sequence of an ancestral β subunit a molecular phylogeny is required, which is inferred from a β subunit sequence alignment. To build this alignment we searched the NCBI database for proteins similar in sequence to the human muscle-type β subunit precursor prot
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The diagnosis of ICP is currently based on the
2023-08-22

The diagnosis of ICP is currently based on the presence of pruritus, raised fasting serum TBS levels above 10μmol/L, and/or elevated serum transaminases (in the absence of diseases that cause cholestasis or pruritus) as well as spontaneous relief of signs and symptoms within four to six weeks after
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mitoxantrone Many coumarin derivatives can be found in natur
2023-08-22

Many coumarin derivatives can be found in nature. There are more than 1300 types of those purely derived from plants, and if synthetic products are included, their number is immeasurable. According to the earliest existing records extant, herbs containing Psoralen-type compounds, e.g., methoxsalen,
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Similar to the importance of MeJA in postharvest A bisporus
2023-08-22

Similar to the importance of MeJA in postharvest A. bisporus quality maintenance at 10°C storage (Meng et al., 2012a), MeJA was also observed to play a pivotal role in this event at 4°C storage. Cap opening is an important mushroom quality indicator (Braaksma et al., 1999). During postharvest storag
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Hsp also called FK binding protein FKBP is
2023-08-22

Hsp56 (also called FK506-binding protein 52, FKBP52) is one of the steroid receptor-associated immunophilins with tetratricopeptide repeat domains, which serve as binding sites for Hsp90 (Peattie et al., 1992). Hsp56 is elevated in breast cancer compared with normal breast tissue (Ward et al., 1999)
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These experiments make it clear that one can study the
2023-08-22

These experiments make it clear that one can study the effect of antimalaria drugs that target the DHFR enzyme of P. falciparum by transferring the malaria enzyme into S. cerevisiae. The ease of growth and manipulation of the yeast make it easy to measure the sensitivity of any particular dhfr allel
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